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Neetu Singh Geography Notes Pdf 14 2021 ⭢

August 31, 2022

Neetu Singh Geography Notes Pdf 14 2021 ⭢


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Neetu Singh Geography Notes Pdf 14

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Water-soluble proteins (WSPs) are a class of recombinant protein products obtained from various means (e.g., bacterial fermentation, yeast fermentation, mammalian cell culture, insect cell culture, transgenic animals, transgenic plants, etc.) that are typically comprised of either a WSP itself or portions of a WSP. WSPs can be used as pharmaceuticals, diagnostic kits, or nutritional supplements. However, particularly in the case of WSPs produced by recombinant means, there is a need to thoroughly characterize such proteins (e.g., composition and activity) prior to use, and additionally, there is a need to be able to adequately process and store such proteins for later use.
One class of WSPs that is currently in clinical trials or is available on the market are various WSPs derived from breast milk including, but not limited to human serum albumin (HSA), lactoferrin, lysozyme, a 1-8 beta lactoglobulin fragment, the alpha-lactalbumin fragment and the R domain of human lactoferrin. These different WSPs have very different physical/chemical properties and therefore require appropriate extraction, purification and characterization in order to produce consistent therapeutics or diagnostic kits. In the case of breast milk-derived WSPs, safe and effective extraction and characterization methods are particularly important, since such methods may be used to harvest infant formula.
In particular, various proteins from human breast milk have been shown to offer protection against certain bacterial strains in breast fed infants. For example, it is known that human breast milk contains a variety of lysozyme, lactoferrin and lipocalin proteins that can have bactericidal or bacteriostatic properties. Also, various WSPs (e.g., lactoferrin) have been reported to have the ability to influence the immune system of infants as well as

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